PLoS ONE (Jan 2018)

In-vivo and numerical analysis of the eigenmodes produced by a multi-level Tic-Tac-Toe head transmit array for 7 Tesla MRI.

  • Tales Santini,
  • Yujuan Zhao,
  • Sossena Wood,
  • Narayanan Krishnamurthy,
  • Junghwan Kim,
  • Nadim Farhat,
  • Salem Alkhateeb,
  • Tiago Martins,
  • Minseok Koo,
  • Tiejun Zhao,
  • Howard J Aizenstein,
  • Tamer S Ibrahim

DOI
https://doi.org/10.1371/journal.pone.0206127
Journal volume & issue
Vol. 13, no. 11
p. e0206127

Abstract

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Radio-frequency (RF) field inhomogeneities and higher levels of specific absorption rate (SAR) still present great challenges in ultrahigh-field (UHF) MRI. In this study, an in-depth analysis of the eigenmodes of a 20-channel transmit Tic-Tac-Toe (TTT) RF array for 7T neuro MRI is presented. The eigenmodes were calculated for five different Z levels (along the static magnetic field direction) of the coil. Four eigenmodes were obtained for each Z level (composed of 4 excitation ports), and they were named based on the characteristics of their field distributions: quadrature, opposite-phase, anti-quadrature, and zero-phase. Corresponding finite-difference time-domain (FDTD) simulations were performed and experimental B1+ field maps were acquired using a homogeneous spherical phantom and human head (in-vivo). The quadrature mode is the most efficient and it excites the central brain regions; the opposite-phase mode excites the brain peripheral regions; anti-quadrature mode excites the head periphery; and the zero-phase mode excites cerebellum and temporal lobes. Using this RF array, up to five eigenmodes (from five different Z levels) can be simultaneously excited. The superposition of these modes has the potential to produce homogeneous excitation with full brain coverage and low levels of SAR at 7T MRI.