Clinical Case Reports (Dec 2020)

Pasireotide‐induced hyperglycemia in a patient with Cushing's disease: Potential use of sodium‐glucose cotransporter 2 inhibitor and glucagon‐like peptide‐1 receptor agonist for treatment

  • Masato Shikata,
  • Kenji Ashida,
  • Yuka Goto,
  • Ayako Nagayama,
  • Shimpei Iwata,
  • Mamiko Yano,
  • Nao Hasuzawa,
  • Kento Hara,
  • Kazutoshi Mawatari,
  • Kiyohiko Sakata,
  • Munehisa Tsuruta,
  • Nobuhiko Wada,
  • Masatoshi Nomura

DOI
https://doi.org/10.1002/ccr3.3230
Journal volume & issue
Vol. 8, no. 12
pp. 2613 – 2618

Abstract

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Abstract Pasireotide improves hypercortisolemia and induces hyperglycemia via somatostatin receptor type‐5 stimulation. GLP‐1RA and SGLT2 inhibitor potentially help regulate hyperglycemia in patients with Cushing's disease, especially after pasireotide administration.

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