Risk factors for postoperative delirium after rectal cancer resection in non-diabetic elderly patients

Abstract

Objective To investigate the risk factors for postoperative delirium (POD) after rectal cancer resection in non-diabetic elderly patients. Methods The clinical data of 542 patients were collected from the Perioperative Neurocognitive Disorder Risk Factor and Prognosis study, and according to the presence or absence of POD, they were divided into POD group with 80 patients and non-POD group with 462 patients. The two groups were compared in terms of sex, age, years of education, fasting blood glucose (FBG) before surgery, glycosylated hemoglobin before surgery, Mini-Mental State Examination (MMSE) score before surgery, and the presence or absence of POD, and the logistic regression model was used to investigate the influencing factors for POD in patients. Results The incidence rate of POD was 14.8% among these patients. There were significant diffe-rences between the POD group and the non-POD group in age, years of education, preoperative FBG level, and preoperative MMSE score (t=-5.420,-2.121,Z=-12.691,-7.753,P<0.05). The logistic regression analysis showed that the increase in preoperative FBG level (OR=1.149,95%CI=1.012-1.305,P<0.05) was a risk factor for POD. Conclusion The increase in preoperative FBG level is one of the risk factors for POD in non-diabetic patients after rectal cancer resection.

Keywords

• delirious speech|postoperative complications|rectal neoplasms|blood glucose|fasting|root cause ana-lysis