Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing

Ipshita Zutshi; Maylin L. Fu; Varoth Lilascharoen; Jill K. Leutgeb; Byung Kook Lim; Stefan Leutgeb

doi:10.1038/s41467-018-06104-5

Nature Communications (Sep 2018)

Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing

Ipshita Zutshi,
Maylin L. Fu,
Varoth Lilascharoen,
Jill K. Leutgeb,
Byung Kook Lim,
Stefan Leutgeb

Affiliations

Ipshita Zutshi: Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego
Maylin L. Fu: Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego
Varoth Lilascharoen: Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego
Jill K. Leutgeb: Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego
Byung Kook Lim: Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego
Stefan Leutgeb: Neurobiology Section and Center for Neural Circuits and Behavior, Division of Biological Sciences, University of California, San Diego

DOI: https://doi.org/10.1038/s41467-018-06104-5
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 15

Abstract

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Medial entorhinal cortex (mEC) neurons encode various navigation parameters such as speed, head direction, as well as grid cells. Here, the authors demonstrate that brief disruption of the local activity in mEC specifically affects grid cell tuning.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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