Chronic cough in a patient with nonerosive reflux disease: a clinical case

Abstract

Chronic cough associated with reflux is one of the extraesophageal manifestations of gastroesophageal reflux disease (GERD), and in some cases may be the leading or only manifestation of GERD. This article presents a clinical case of a patient with chronic cough, who, during the examination, was diagnosed with GERD, extraesophageal manifestations, reflux-associated cough. The use of the Reflux Symptom Index (RSI) questionnaire has helped in the diagnosis of laryngopharyngeal reflux. The absence of convincing evidence of GERD according to esophagogastroduodenoscopy was an indication for 24-hour pH impedance measurements, which made it possible to confirm the diagnosis. Lifestyle modification and combination therapy with rabeprazole and rebamipide are an effective approach in the treatment of extraesophageal manifestations of non-erosive reflux disease in the form of reflux-associated cough.

Keywords

• gastroesophageal reflux disease
• cough
• ph-impedance monitoring
• h. pylori
• rabeprazole
• rebamipide