Rapid, enantioselective and colorimetric detection of D-arginine
Xianzhe Yu,
Binjie Zhang,
Cailing Fan,
Qianqian Yan,
Shenglin Wang,
Hui Hu,
Qinxi Dong,
Gengyu Du,
Yanan Gao,
Chaoyuan Zeng
Affiliations
Xianzhe Yu
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Binjie Zhang
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Cailing Fan
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Qianqian Yan
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Shenglin Wang
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Hui Hu
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Qinxi Dong
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China
Gengyu Du
Department of Chemistry, University of Virginia, Charlottesville, VA 22904, USA; Corresponding author
Yanan Gao
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China; Corresponding author
Chaoyuan Zeng
Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Collaborative Innovation Center of Ecological Civilization, Hainan University, No 58, Renmin Avenue, Haikou 570228, China; Corresponding author
Summary: D-amino acids are of biological significance yet are not clearly understood due to the lack of powerful analytical tools for their identification. Thus, the specific detection of a single enantiomer of a particular amino acid remains a great challenge due to their structural similarity. Here, we report a strategy to incorporate multiple reaction sites on a chiral 1,1′-bi-2,2′-naphthol-based fluorescent probe. It can respond specifically to D-arginine, while producing no response when in contact with all other amino acids. The probe can report arginine’s concentration, and enantiomeric configuration and colorimetric studies enable its qualitative determination.
