CHRONIC VIRAL HEPATITIS В AND C IN CHILDREN BORN FROM MOTHERS INFECTED WITH НВV AND HCV

Abstract

There were 164 children with chronic hepatitis B (CHB) and chronic hepatitis C (CHC) at the age of 1—18 years of age, 78 of which (48%) had a perinatal route of infection (CHB — 46; CHC — 32). Observed for 5 years. Chronic hepatitis B and C was characterized by subclinical signs, with minimal fibrosis, in the immu- noactive phase of HBV (69%) and high viremia HCV (56%). Etiopathogenetic therapy (alpha-2b interferon (VIFERON, PegIntron), lamivudine (Zeffix), ribavirin (Rebetol) promoted the development of clinico-virologic remission in 83% of children with CHB and 63% in CHC.

Keywords

• children
• viral hepatitis b
• viral hepatitis c
• hbv
• hcv
• perinatal infection