Physical exercise and arrhythmogenic right ventricular cardiomyopathy/dysplasia: An overview

Abstract

Arrhythmogenic right ventricular cardiomyopathy/dysplasia is inherited cardiomyopathy that has a propensity for ventricular arrhythmia, ventricular dysfunction, and sudden cardiac death. High-intensity exercise is associated with early disease manifestation and increased risk of malignant arrhythmia and sudden death. Exercise restriction should be advised as an integral part of disease management. This overview summarizes the medical literature on the impact of exercise in triggering ventricular arrhythmias and disease progression.

Keywords

• arrhythmogenic cardiomyopathy
• desmosomal mutation
• dysplasia
• exercise
• metabolic equivalent
• plakophilin-2