Journal of Rawalpindi Medical College (Mar 2015)
Patterns of Dyslipidaemia in Prehypertensive and Normotensive Subjects
Abstract
Background: To study trends in levels of lipids in prehypertensive and normotensive people. Methods: In this cross sectional study a total of 90 apparently healthy subjects with age being 30-59 years and without any other illness were selected. Blood pressure was monitored and categorised into normotensive group 1 (n-39) and prehypertensive group 2 (n=39). Any volunteer with raised blood sugar was excluded from the study. Their blood was collected and sera was seperated after ultracentrifugation to analyze triglycerides, total cholesterol, LDL and HDL. Independent student t-test (2-tailed) was applied in order to compare difference between selected variables such as age, BMI, total cholesterol, LDL, HDL and triglycerides of normotensives and prehypertensive groups. Results: Mean values of serum cholesterol, serum LDL, serum HDL and serum triglycerides were higher in prehypertensives than normotensives. Serum HDL was found to be relatively low in all subjects regardless of their blood pressure levels. No difference in demographic variables were found amongst two groups and were found within range. Conclusion: Mean serum lipids were found to be raised in prehypertensives than normotensives but difference was statistically insignificant.Frequencies and percentages of serum lipids were higher in prehypertensives than normotensives but difference was statistically insignificant.