A natural riboswitch scaffold with self-methylation activity

Laurin Flemmich; Sarah Heel; Sarah Moreno; Kathrin Breuker; Ronald Micura

doi:10.1038/s41467-021-24193-7

Nature Communications (Jun 2021)

A natural riboswitch scaffold with self-methylation activity

Laurin Flemmich,
Sarah Heel,
Sarah Moreno,
Kathrin Breuker,
Ronald Micura

Affiliations

Laurin Flemmich: University of Innsbruck, Institute of Organic Chemistry and Center for Molecular Biosciences (CMBI)
Sarah Heel: University of Innsbruck, Institute of Organic Chemistry and Center for Molecular Biosciences (CMBI)
Sarah Moreno: University of Innsbruck, Institute of Organic Chemistry and Center for Molecular Biosciences (CMBI)
Kathrin Breuker: University of Innsbruck, Institute of Organic Chemistry and Center for Molecular Biosciences (CMBI)
Ronald Micura: University of Innsbruck, Institute of Organic Chemistry and Center for Molecular Biosciences (CMBI)

DOI: https://doi.org/10.1038/s41467-021-24193-7
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 10

Abstract

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In humans, protein methyltransferase is responsible for RNA methylation using S-adenosylmethionine as a methyl group donor. Here the authors report a self-methylation activity of a bacterial riboswitch.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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