N-Sulfonyl Amino Acid Amides, a Novel Class of Compounds with Fungicidal Activity [1]

Abstract

Novel types of oomycete fungicides have been designed and prepared. The synthetic approach to these N-sulfonyl amino acid amides is outlined. Bioassays demonstrate their high efficacy against important plant diseases like Phytophthora infestans (tomato and potato late blight) and Plasmopara viticola (grape downy mildew). Structure–activity relationship studies are discussed.

Keywords

• Amino acid derivative
• Fungicide
• Phytophthora infestans
• Plasmopara viticola
• Ugi reaction
• Valinamide