Nature Communications (Apr 2021)
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
- William S. Harris,
- Nathan L. Tintle,
- Fumiaki Imamura,
- Frank Qian,
- Andres V. Ardisson Korat,
- Matti Marklund,
- Luc Djoussé,
- Julie K. Bassett,
- Pierre-Hugues Carmichael,
- Yun-Yu Chen,
- Yoichiro Hirakawa,
- Leanne K. Küpers,
- Federica Laguzzi,
- Maria Lankinen,
- Rachel A. Murphy,
- Cécilia Samieri,
- Mackenzie K. Senn,
- Peilin Shi,
- Jyrki K. Virtanen,
- Ingeborg A. Brouwer,
- Kuo-Liong Chien,
- Gudny Eiriksdottir,
- Nita G. Forouhi,
- Johanna M. Geleijnse,
- Graham G. Giles,
- Vilmundur Gudnason,
- Catherine Helmer,
- Allison Hodge,
- Rebecca Jackson,
- Kay-Tee Khaw,
- Markku Laakso,
- Heidi Lai,
- Danielle Laurin,
- Karin Leander,
- Joan Lindsay,
- Renata Micha,
- Jaako Mursu,
- Toshiharu Ninomiya,
- Wendy Post,
- Bruce M. Psaty,
- Ulf Risérus,
- Jennifer G. Robinson,
- Aladdin H. Shadyab,
- Linda Snetselaar,
- Aleix Sala-Vila,
- Yangbo Sun,
- Lyn M. Steffen,
- Michael Y. Tsai,
- Nicholas J. Wareham,
- Alexis C. Wood,
- Jason H. Y. Wu,
- Frank Hu,
- Qi Sun,
- David S. Siscovick,
- Rozenn N. Lemaitre,
- Dariush Mozaffarian,
- The Fatty Acids and Outcomes Research Consortium (FORCE)
Affiliations
- William S. Harris
- Department of Internal Medicine, Sanford School of Medicine, University of South Dakota
- Nathan L. Tintle
- The Fatty Acid Research Institute
- Fumiaki Imamura
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Frank Qian
- Department of Nutrition, Harvard T.H. Chan School of Public Health and Harvard Medical School
- Andres V. Ardisson Korat
- Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School
- Matti Marklund
- The George Institute for Global Health and the Faculty of Medicine, University New South Wales
- Luc Djoussé
- Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School
- Julie K. Bassett
- Cancer Epidemiology Division, Cancer Council Victoria
- Pierre-Hugues Carmichael
- Centre D’excellence Sur le Vieillissement de Québec, CIUSSS-CN
- Yun-Yu Chen
- Department of Medicine, Taipei Veterans General Hospital; and Institute of Epidemiology and Preventive Medicine, National Taiwan University
- Yoichiro Hirakawa
- Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
- Leanne K. Küpers
- Division of Human Nutrition and Health, Wageningen University
- Federica Laguzzi
- Institute of Environmental Medicine, Karolinska Institute
- Maria Lankinen
- Institute of Public Health and Clinical Nutrition, University of Eastern Finland
- Rachel A. Murphy
- Cancer Control Research, BC Cancer Agency; and School of Population and Public Health, University of British Columbia
- Cécilia Samieri
- Bordeaux Population Health Research Centre, INSERM, University of Bordeaux
- Mackenzie K. Senn
- USDA/ARS Children’s Nutrition Research Center, Baylor College of Medicine
- Peilin Shi
- Freidman School of Nutrition Science and Policy, Tufts University
- Jyrki K. Virtanen
- Institute of Public Health and Clinical Nutrition, University of Eastern Finland
- Ingeborg A. Brouwer
- Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam and Amsterdam Public Health Research Institute
- Kuo-Liong Chien
- Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University
- Gudny Eiriksdottir
- Icelandic Heart Association
- Nita G. Forouhi
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Johanna M. Geleijnse
- Division of Human Nutrition and Health, Wageningen University
- Graham G. Giles
- Centre for Epidemiology and Biostatistics, The University of Melbourne
- Vilmundur Gudnason
- Icelandic Heart Association
- Catherine Helmer
- Bordeaux Population Health Research Centre, INSERM, University of Bordeaux
- Allison Hodge
- Centre for Epidemiology and Biostatistics, The University of Melbourne
- Rebecca Jackson
- Department of Internal Medicine, Division of Endocrinology, The Ohio State University
- Kay-Tee Khaw
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Markku Laakso
- Institute of Clinical Medicine, University of Eastern Finland
- Heidi Lai
- Freidman School of Nutrition Science and Policy, Tufts University
- Danielle Laurin
- Centre D’excellence Sur le Vieillissement de Québec, CIUSSS-CN
- Karin Leander
- Institute of Environmental Medicine, Karolinska Institute
- Joan Lindsay
- School of Epidemiology and Public Health, University of Ottawa
- Renata Micha
- Freidman School of Nutrition Science and Policy, Tufts University
- Jaako Mursu
- Institute of Public Health and Clinical Nutrition, University of Eastern Finland
- Toshiharu Ninomiya
- Department of Epidemiology and Public Health, Kyushu University
- Wendy Post
- Cancer Epidemiology Division, Cancer Council Victoria
- Bruce M. Psaty
- Cardiovascular Health Research Unit, Department of Medicine, University of Washington
- Ulf Risérus
- Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University
- Jennifer G. Robinson
- Department of Medicine, University of Iowa
- Aladdin H. Shadyab
- Department of Family Medicine and Public Health, University of California San Diego School of Medicine
- Linda Snetselaar
- Department of Epidemiology, University of Iowa
- Aleix Sala-Vila
- The Fatty Acid Research Institute
- Yangbo Sun
- Department of Epidemiology, University of Iowa
- Lyn M. Steffen
- School of Public Health, Division of Epidemiology and Community Health, University of Minnesota
- Michael Y. Tsai
- Department of Laboratory Medicine and Pathology, University of Minnesota
- Nicholas J. Wareham
- MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine
- Alexis C. Wood
- USDA/ARS Children’s Nutrition Research Center, Baylor College of Medicine
- Jason H. Y. Wu
- The George Institute for Global Health and the Faculty of Medicine, University New South Wales
- Frank Hu
- Department of Nutrition, Harvard T.H. Chan School of Public Health and Harvard Medical School
- Qi Sun
- Department of Nutrition, Harvard T.H. Chan School of Public Health and Harvard Medical School
- David S. Siscovick
- The New York Academy of Medicine
- Rozenn N. Lemaitre
- Cardiovascular Health Research Unit, Department of Medicine, University of Washington
- Dariush Mozaffarian
- Freidman School of Nutrition Science and Policy, Tufts University
- The Fatty Acids and Outcomes Research Consortium (FORCE)
- DOI
- https://doi.org/10.1038/s41467-021-22370-2
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 9
Abstract
Associations between of omega-3 fatty acids and mortality are not clear. Here the authors report that, based on a pooled analysis of 17 prospective cohort studies, higher blood omega-3 fatty acid levels correlate with lower risk of all-cause mortality.
