Медицинская иммунология (Jul 2014)

ADVANCES AND PERSPECTIVES OF CLINICAL ABZYMOLOGY

  • S. V. Suchkov,
  • Z. S. Alekberova,
  • A. N. Hitrov,
  • Z. S. Shogenov,
  • O. V. Voskresenskaya,
  • N. V. Gnuchev,
  • A. G. Gabibov

DOI
https://doi.org/10.15789/1563-0625-2006-1-23-30
Journal volume & issue
Vol. 8, no. 1
pp. 23 – 30

Abstract

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Abstract. Natural catalytic autoantibodies (abzymes) posessing proteolytic (protoabzymes) and DNA-hydrolysing (DNA-abzymes) activities are detectable in clinical and experimental autoimmune disorders. Catalytic activity of abzymes is revealed in the patients with different forms of systemic (nonspecific) and organ-specific autoimmune pathology. The opportunity of assaying the abzymes for intensity monitoring of autoimmune disease is also described.

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