Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors

Abstract

Introduction The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors. Material and methods A total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with 65 years were characterized by G1-2, higher lymphocyte values, lower platelet (PLT) counts and lower NLR or PLR values than patients 65 years is a negative prognostic factor independent of other factors.

Keywords

• breast cancer
• neutrophil-to-lymphocyte ratio
• platelet-to-lymphocyte ratio
• platelet
• brca
• checkpoint kinase 2
• nucleotide binding oligomerization domain containing 2 mutation