Synthesis and Wittig Rearrangement of 3- and 4-Benzyloxyphenylphosphonamidates

Abstract

A series of seven O-ethyl-N-butylphenylphosphonamidates with benzyl ether substituents at the para or meta position have been prepared and fully characterised. Upon treatment with n-butyllithium in THF at RT, these undergo Wittig rearrangement in six cases to give the novel phosphonamidate-substituted diarylmethanols in moderate to good yield.

Keywords

• Wittig rearrangement
• phosphonamidate
• diarylmethanol
• aryl benzyl ether