Nuclear Morphometry of Perimenopausal Endometrium in Nepali Population

Abstract

Cytoarchitecture of the endometrium is an important tool for the diagnosis of precancerous state to carcinoma. In which, one of the most significant feature is nuclear morphology and morphometry. Present study was aimed to report the morphology and morphometry of perimenopausal endometrium because this age group is vulnerable to precancerous state to carcinoma. 204 cases were studied. Our study result showed, mean nuclear diameter was 5 µm, proliferative phase 4.75 µm and secretary phase 5 µm. There was much variation observed in the secretary phase endometrium: early-6 µm and both mid and late stage observed 5 µm. Morphology of endometrium reflected the precancerous state in sixteen cases.

Keywords

• Endometrium
• Perimenopausal age
• Nucleus
• Morphometry