Description of “Tail Suspension” as a Model of ‹mmobilization in Rats

Abstract

Since human beings have included outer space to their living places, effects of gravity on bone has been extensively studied. Authors claim that basic biologic mechanisms are similar in rats and human so rats should serve as a useful model for studying osteoporosis. Models for simulating microgravity conditions can be grouped into two as local and systemic models. We aimed to summarize models for immobilization as well as detailed description of tail suspension model.

Keywords

• immobilization
• rat
• tail suspension model
• osteoporosis