Results of clinical studies PLATO and place of ticagrelor in the treatment of acute coronary syndrome

Abstract

This article provides an analysis of the results of a large international randomized clinical trial PLATO, in which to learn a new antiplatelet ticagrelor compared with clopidogrel in addition to aspirin in patients with acute coronary syndrome (ACS). Material contains a description of the study design, the main results concerning the efficacy and safety of ticagrelor. In addition, the material presented those parts of modern clinical practice guidelines, which describes the location of ticagrelor in the treatment of ACS and which are modified according to a PLATO study.

Keywords

• plato
• acute coronary syndrome
• ticagrelor
• clopidogrel
• plato