Application of nonsteroidal anti-inflammatory drugs in aortic aneurysm

Abstract

INTRODUCTION: Aortic aneurysms have among their main factor for rupture, growth, produced by the weakening of the aneurysmal wall influenced by different risk factors. MATERIAL AND METHOD: A 5-year investigation was carried out with a group of 63 patients with aortic aneurysms who, for different reasons, were not operated on during the study period. They were divided into two groups, one called a study with 48 patients and another with 15 who use in the study group, ibuprofen-based medical treatment (non-steroidal anti-inflammatory drugs [NSAIDs) in doses of 800 mg per day and sixmonthly ultrasound controls throughout the period of the investigation, measuring the aneurysmal diameters to demonstrate the growth, detection or reduction of the same. RESULTS: The usefulness and efficacy of the use of NSAIDs in the field of medical treatment of aortic aneurysms was demonstrated, since during the investigation of the two study groups, we achieved higher survival rates for the group treated with NSAIDs. CONCLUSIONS: Through growth control as the main rupture factor and therefore a complication that in most cases is fatal, we achieved a reduction in the aneurysmal diameter in a number of patients with higher survival rates than in the control group. Graphs up to 5 years are presented that support the results achieved.

Keywords

• aortic aneurysm
• application
• nonsteroidal anti-inflammatory drugs