Rapid sustainable synthesis of Mn2O3, CuO, and binary CuO/Mn2O3 nanoparticles using continuous laser diode for enhanced antibacterial strategy against resistant pathogens

Abstract

Substantial health issues have recently resulted from the sharp rise of antibiotic-resistant bacteria. Researchers are looking for substitute antimicrobial agents to manage or stop pathogen-induced illnesses. Effective antibacterial drugs are developed using a variety of techniques, and nanoscale is definitely a promising substance in this regard. In this work, it was provided a unique quick sustainable synthesis approach of Mn2O3, CuO and CuO/Mn2O3 using a continuous laser diode (CLD). Manganese (II) acetate, deionized water|(DW), and sodium hydroxide (NaOH) are used to prepare a gelatinous solution of Manganese (II) hydroxide Mn(OH)2. A gelatinous solution of Mn(OH)2 was poured into a circular plate and then it was bombarded by a continuous laser diode. A black powder of Mn2O3 nanoparticles was obtained. The nanoparticles were characterized using various techniques such as Scanning electron microscope (SEM), transmitted electron microscope (TEM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR). XRD results of the MnO2 nanoparticles show a high degree of crystallinity. The average particle size of 38 [nm] can be observed for samples prepared at time 30 min was determined by SEM and 30 nm by TEM. Mn2O3, CuO and CuO/Mn2O3 nanoparticles were used for decontamination and inactivation of Escherichia coli, Staphylococcus, pseudomonas and Candid strain clinical isolates as an alternative sterilization method. The Antibacterial activity shows that Mn2O3 has a minimum activity while CuO and CuO/Mn2O3 are more influential. The conclusion considered a new direct way to synthesize of Mn2O3, CuO, and CuO/Mn2O3 nanoparticles that is employed in many scientific applications.

Keywords

• Binary CuO/ Mn2O3 nanoparticles
• Escherichia coli
• Continuous laser diode
• Antibacterial activity
• Rapid sustainable synthesis