Pathophysiology and treatment strategies for COVID-19

Abstract

Abstract The outbreak of Coronavirus disease of 2019 (COVID-19) caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), has posed a serious health threat. The increasing number of COVID-19 cases around the world is overwhelming hospitals and pushing the global death toll to over 746,000, which has pushed the sprint to find new treatment options. In this article, we reviewed the SARS-CoV-2 pathophysiology, transmission, and potential treatment strategies.

Keywords

• SARS-CoV-2
• Pandemic
• 2019 novel coronavirus
• Viral inhibitor
• ACE-2 receptor
• Receptor binding protein