Portable Biomedical System for Acquisition, Display and Analysis of Cardiac Signals (SCG, ECG, ICG and PPG)

Abstract

This study introduces a mechatronic biomedical device engineered for concurrent acquisition and analysis of four cardiac non-invasive signals: Electrocardiogram (ECG), Phonocardiogram (PCG), Impedance Cardiogram (ICG), and Photoplethysmogram (PPG). The system enables assessment of individual and simultaneous waveforms, allowing for detailed scrutiny of cardiac electrical and mechanical dynamics, encompassing heart rate variability, systolic time intervals, pre-ejection period (PEP), and aortic valve opening and closing timings (ET) through an application programmed with MATLAB App Designer, which applies derivative filters, smoothing, and FIR digital filters and evaluates the delay of each one, allowing the synchronization of all signals. These metrics are indispensable for deriving critical hemodynamic indices such as Stroke Volume (SV) and Cardiac Output (CO), paramount in the diagnostic armamentarium against cardiovascular pathologies. The device integrates an assembly of components including five electrodes, operational and instrumental amplifiers, infrared opto-couplers, accelerometers, and advanced filtering subsystems, synergistically tailored for precision and fidelity in signal processing. Rigorous validation utilizing a cohort of healthy subjects and benchmarking against established commercial instrumentation substantiates an accuracy threshold below 4.3% and an Interclass Correlation Coefficient (ICC) surpassing 0.9, attesting to the instrument’s exceptional reliability and robustness in quantification. These findings underscore the clinical potency and technical prowess of the developed device, empowering healthcare practitioners with an advanced toolset for refined diagnosis and management of cardiovascular disorders.

Keywords

• cardiovascular disease
• cardiac signal
• ECG
• SCG
• ICG
• PPG