Usual interstitial pneumonia progressing to nonspecific interstitial pneumonia-like pattern on high-resolution CT with histologic confirmation

Kai Yazaki, MD; Mizu Nonaka, MD; Rie Shigemasa, MD; Yuko Minami, MD, PhD; Takefumi Saito, MD, PhD; Nobuyuki Hizawa, MD, PhD

Radiology Case Reports (May 2021)

Usual interstitial pneumonia progressing to nonspecific interstitial pneumonia-like pattern on high-resolution CT with histologic confirmation

Kai Yazaki, MD,
Mizu Nonaka, MD,
Rie Shigemasa, MD,
Yuko Minami, MD, PhD,
Takefumi Saito, MD, PhD,
Nobuyuki Hizawa, MD, PhD

Affiliations

Kai Yazaki, MD: Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokai, Japan; Department of Pulmonary Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan; Corresponding author.
Mizu Nonaka, MD: Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokai, Japan; Department of Pulmonary Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Rie Shigemasa, MD: Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokai, Japan; Department of Pulmonary Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan
Yuko Minami, MD, PhD: Department of Pathology, National Hospital Organization, Ibarakihigashi National Hospital, Tokai, Japan
Takefumi Saito, MD, PhD: Department of Respiratory Medicine, National Hospital Organization, Ibarakihigashi National Hospital, Tokai, Japan
Nobuyuki Hizawa, MD, PhD: Department of Pulmonary Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan

Journal volume & issue: Vol. 16, no. 5
pp. 1019 – 1022

Abstract

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Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease. Although high-resolution computed tomography (HRCT) is important for the diagnosis of IPF, the changes in the HRCT findings in IPF are not fully understood. The patient was a 66-year-old man. His HRCT findings had atypically developed from a probable usual interstitial pneumonia pattern to a nonspecific interstitial pneumonia (NSIP) like pattern over 6 years. On the basis of the histologic examination and multidisciplinary discussion, IPF was diagnosed, and nintedanib, administered. This case can be useful for the differential diagnosis of IPF and NSIP.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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