Journal of Mind and Medical Sciences (Oct 2023)

Giant renal cell carcinoma in a patient with ipsilateral lower limb hypertrophic lichen planus; Case r ophic lichen planus; Case report and liter t and literature review

  • Silvia Popescu,
  • Dumitru Peța,
  • Zoltan Janos Kövér,
  • Dumitru Toma,
  • Ioan-Teodor Cristea,
  • Mihaela Anca Popescu,
  • Oana-Denisa Bălălău,
  • Romina-Marina Sima,
  • Gabriel-Petre Gorecki,
  • Călin Giurcăneanu

DOI
https://doi.org/10.22543/2392-7674.1425
Journal volume & issue
Vol. 10, no. 2
pp. 356 – 363

Abstract

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Renal cell carcinoma is the most common type of primary urogenital cancer, usually resistant to radiotherapy and chemotherapy. Hypertrophic lichen planus is an inflammatory dermatosis characterized by the presence of papulosquamous and intensely pruritic lesions. The association of these two conditions is unusual, being reported in the specialized literature only in a few rare cases with the onset of lichenoid lesions after patients have undergone various forms of treatment. The case of a 62-year-old male patient who was admitted for severe abdominal pain due to a giant renal tumor associated with a hypertrophic plaque located on the anterior part of the left calf is presented. After (clinical, biochemical, imaging) diagnosis, surgery was performed for en bloc removal of the entire mass, adrenal gland, and spleen. The histopathological exam established the diagnosis of a moderately differentiated T2b clear cell Grawitz tumor, without regional lymph node metastasis (stage II). The patient continued local corticosteroid therapy in the hospital for hypertrophic lichen planus lesions, being referred to the oncology department after discharge.

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