Nature Communications (Oct 2020)

Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy

  • Ying Jing,
  • Jin Liu,
  • Youqiong Ye,
  • Lei Pan,
  • Hui Deng,
  • Yushu Wang,
  • Yang Yang,
  • Lixia Diao,
  • Steven H. Lin,
  • Gordon B. Mills,
  • Guanglei Zhuang,
  • Xinying Xue,
  • Leng Han

DOI
https://doi.org/10.1038/s41467-020-18742-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 7

Abstract

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Immunotherapy, the reactivation of the immune system to recognize cancer cells, can be accompanied by severe adverse effects. Here, the authors use pharmacovigilance and genomic data to be able to predict which patients might be susceptible to such severe events.