Identification and Molecular Dissection of IMC32, a Conserved
<i>Toxoplasma</i>
Inner Membrane Complex Protein That Is Essential for Parasite Replication
Juan A. Torres,
Rebecca R. Pasquarelli,
Peter S. Back,
Andy S. Moon,
Peter J. Bradley
Affiliations
Juan A. Torres
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
Rebecca R. Pasquarelli
Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA
Peter S. Back
Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA
Andy S. Moon
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
The IMC is an important organelle that apicomplexan parasites use to maintain their intracellular lifestyle. While many IMC proteins have been identified, only a few central players that are essential for internal budding have been described and even fewer are conserved across the phylum.
