Identification and Molecular Dissection of IMC32, a Conserved
<i>Toxoplasma</i>
Inner Membrane Complex Protein That Is Essential for Parasite Replication

Juan A. Torres; Rebecca R. Pasquarelli; Peter S. Back; Andy S. Moon; Peter J. Bradley

doi:10.1128/mBio.03622-20

mBio (Feb 2021)

Identification and Molecular Dissection of IMC32, a Conserved <i>Toxoplasma</i> Inner Membrane Complex Protein That Is Essential for Parasite Replication

Juan A. Torres,
Rebecca R. Pasquarelli,
Peter S. Back,
Andy S. Moon,
Peter J. Bradley

Affiliations

Juan A. Torres: Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
Rebecca R. Pasquarelli: Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA
Peter S. Back: Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA
Andy S. Moon: Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA
Peter J. Bradley: ORCiD; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, USA

DOI: https://doi.org/10.1128/mBio.03622-20
Journal volume & issue: Vol. 12, no. 1

Abstract

Read online

The IMC is an important organelle that apicomplexan parasites use to maintain their intracellular lifestyle. While many IMC proteins have been identified, only a few central players that are essential for internal budding have been described and even fewer are conserved across the phylum.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal