Nature Communications (Jun 2018)

A novel atypical sperm centriole is functional during human fertilization

  • Emily L. Fishman,
  • Kyoung Jo,
  • Quynh P. H. Nguyen,
  • Dong Kong,
  • Rachel Royfman,
  • Anthony R. Cekic,
  • Sushil Khanal,
  • Ann L. Miller,
  • Calvin Simerly,
  • Gerald Schatten,
  • Jadranka Loncarek,
  • Vito Mennella,
  • Tomer Avidor-Reiss

DOI
https://doi.org/10.1038/s41467-018-04678-8
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 12

Abstract

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The two zygote centrioles are paternally inherited; however, their development is incompletely understood. Here, the authors show that the distal centriole is remodeled into an atypical centriole which functions as the zygote’s second centriole.