China Anti-Cancer Association guideline for diagnosis and treatment of cancer of multiple and unknown primaries (2023 edition)

Abstract

Cancer of unknown primary (CUP) and cancer of multiple primaries (CMP) are two groups of neoplasm with high heterogeneity, low incidence, limited clinical knowledge and evidence. The diagnosis and treatment of patients with CUP and CMP is challenging. With the progress in the radiology, pathology and genetic features of these diseases, the cooperation and development of multi-disciplinary treatment, along with the investigation of targeted and immunology treatment have updated the treatment of these patients. We intended to guide the diagnosis and treatment of patients with CUP and CMP through this guideline, providing standard guidance for the overall management of patients.

Keywords

• |cancer of unknown primary|cancer of multiple primaries|diagnosis|treatment|guideline