Draft genome sequence of Staphylococcus hominis strain Hudgins isolated from human skin implicates metabolic versatility and several virulence determinants
Shelby Calkins,
M.B. Couger,
Colin Jackson,
Jordan Zandler,
Garett C. Hudgins,
Radwa A. Hanafy,
Connie Budd,
Donald P. French,
Wouter D. Hoff,
Noha Youssef
Affiliations
Shelby Calkins
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
M.B. Couger
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Colin Jackson
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Jordan Zandler
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Garett C. Hudgins
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Radwa A. Hanafy
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Connie Budd
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Donald P. French
Department of Integrative Biology, Oklahoma State University, Stillwater, OK, United States
Wouter D. Hoff
Department of Microbiology and Molecular Genetics, Oklahoma State University, Stillwater, OK, United States
Noha Youssef
1110 S Innovation way, Stillwater, OK 74074, United States
Staphylococcus hominis is a predominant member of the human skin microbiome. We here report on the genomic analysis of Staphylococcus hominis strain Hudgins that was isolated from the wrist area of human skin. The partial genome assembly of S. hominis Hudgins consists of 2,211,863 bp of DNA with 2174 protein-coding genes and 90 RNA genes. Based on the genomic analysis of KEGG pathways, the organism is expected to be a versatile heterotroph potentially capable of hydrolyzing the sugars glucose, fructose, mannose, and the amino acids alanine, aspartate, glutamate, glycine, threonine, cysteine, methionine, valine, isoleucine, leucine, lysine, arginine, phenylalanine, tyrosine, and tryptophan for energy production through aerobic respiration, with occasional lactate and acetate fermentation. Evidence for poly-gamma glutamate capsule and type IV Com system pili were identified in the genome. Based on COG analysis, the genome of S. hominis Hudgins clusters away from the previously published S. hominis genome ZBW5.
