El déficit de vitamina d se asocia a factores de riesgo en personas sin antecedentes cardiovasculares

Abstract

Resumen El déficit de vitamina D (VitD) se asocia con mayor morbimortalidad. Se evaluó la relación entre el déficit de VitD (140 mmHg y 6% PAD>90 mmHg. El déficit de VitD se observó en el 29.1% (31.3% hombres y 26.1% mujeres, p=0.3), más frecuente en obesos (OR 1.85, IC95:1.05-3.25, p=0.02), en HDL150 mg/dl (OR 1.77, IC95:1.02-3.06, p=0.03). Se observó tendencia a mayor déficit de VitD en TAS>140 mmHg (OR 1.88, IC95:0.93-3.77, p=0.07) y TAD>90 mmHg (OR 1.39, IC95:0.5-3.65, p=0.5). Se observó correlación lineal entre VitD con HDL (p140 mmHg and 6% diastolic blood pressure (DBP) >90 mmHg. VitD deficiency was observed in 29.1% (31.3% man vs 26.1% women, p=0.3), more frequent with obesity (OR 1.85, IC95:1.05-3.25, p=0.02), HDL-cholesterol (HDL-C)150 mg/dl (OR 1.77, IC95:1.02-3.06, p=0.03). A trend towards VitD deficiency and SBP>140 mmHg (OR 1.88, IC95:0.93-3.77, p=0.07) or DBP>90 mmHg (OR 1.39, IC95:0.5-3.65, p=0.5) was observed. Lineal correlation between VitD and HDL-C (p<0.001) or triglycerides (p<0.001) was observed. Multiple logistic regression showed that VitD deficiency association with low HDL-C was independent of age, female sex, obesity and physical activity. Association of VitD deficiency with hypetriglyceridemia was independent of age, female sex and obesity. This study shows an association between VitD deficiency and cardiovascular risk factors like obesity, low HDL <50 mg/dl and hypertriglyceridemia. A trend toward higher SBP was also observed. Experimental studies are granted in order to establish a cause-effect relationship.

Keywords

• Vitamina D
• Colesterol HDL
• Trigliceridos
• Presión Arterial