Scintigraphic load of bone disease evaluated by DASciS software as a survival predictor in metastatic castration-resistant prostate cancer patients candidates to 223RaCl treatment

Frantellizzi Viviana; Pani Arianna; Ippoliti Maria Dea; Farcomeni Alessio; Aloise Irvin; Colosi Mirco; Polito Claudia; Pani Roberto; Vincentis Giuseppe De

doi:10.2478/raon-2019-0058

Radiology and Oncology (Dec 2019)

Scintigraphic load of bone disease evaluated by DASciS software as a survival predictor in metastatic castration-resistant prostate cancer patients candidates to 223RaCl treatment

Frantellizzi Viviana,
Pani Arianna,
Ippoliti Maria Dea,
Farcomeni Alessio,
Aloise Irvin,
Colosi Mirco,
Polito Claudia,
Pani Roberto,
Vincentis Giuseppe De

Affiliations

Frantellizzi Viviana: Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy
Pani Arianna: Postgraduate School of Clinical Pharmacology and Toxicology, University of Milan “Statale”, Milan, Italy
Ippoliti Maria Dea: Department of Radiological Sciences, Oncology and Anatomical Pathology , Sapienza University of Rome, Rome, Italy
Farcomeni Alessio: Department of Public Health and Infectious Diseases, “Sapienza” University of Rome, Rome, Italy
Aloise Irvin: Department of Computer, Control, and Management Engineering Antonio Ruberti, Sapienza University of Rome, Rome, Italy
Colosi Mirco: Department of Computer, Control, and Management Engineering Antonio Ruberti, Sapienza University of Rome, Rome, Italy
Polito Claudia: Specialty School in Medical Physics, Department of Medico-Surgical Sciences and Biotechnologies, University La Sapienza, Rome, Italy
Pani Roberto: Specialty School in Medical Physics, Department of Medico-Surgical Sciences and Biotechnologies, University La Sapienza, Rome, Italy
Vincentis Giuseppe De: Department of Radiological Sciences, Oncology and Anatomical Pathology , Sapienza University of Rome, Rome, Italy

DOI: https://doi.org/10.2478/raon-2019-0058
Journal volume & issue: Vol. 54, no. 1
pp. 40 – 47

Abstract

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Aim of our study was to assess the load of bone disease at starting and during Ra-223 treatment as an overall survival (OS) predictor in metastatic castration-resistant prostate cancer (mCRPC) patients. Bone scan index (BSI) is defined as the percentage of total amount of bone metastasis on whole-body scintigraphic images. We present a specific software (DASciS) developed by an engineering team of “Sapienza” University of Rome for BSI calculation.

Published in Radiology and Oncology

ISSN: 1581-3207 (Online)
Publisher: Sciendo
Country of publisher: Slovenia
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://sciendo.com/journal/RAON

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