Frontiers in Neuroscience (Dec 2022)

Toward a fully implantable ecosystem for adaptive neuromodulation in humans: Preliminary experience with the CorTec BrainInterchange device in a canine model

  • Gerwin Schalk,
  • Gerwin Schalk,
  • Samuel Worrell,
  • Filip Mivalt,
  • Filip Mivalt,
  • Alexander Belsten,
  • Alexander Belsten,
  • Inyong Kim,
  • Jonathan M. Morris,
  • Dora Hermes,
  • Bryan T. Klassen,
  • Nathan P. Staff,
  • Steven Messina,
  • Timothy Kaufmann,
  • Jörn Rickert,
  • Peter Brunner,
  • Peter Brunner,
  • Gregory A. Worrell,
  • Gregory A. Worrell,
  • Kai J. Miller,
  • Kai J. Miller

DOI
https://doi.org/10.3389/fnins.2022.932782
Journal volume & issue
Vol. 16

Abstract

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This article describes initial work toward an ecosystem for adaptive neuromodulation in humans by documenting the experience of implanting CorTec's BrainInterchange (BIC) device in a beagle canine and using the BCI2000 environment to interact with the BIC device. It begins with laying out the substantial opportunity presented by a useful, easy-to-use, and widely available hardware/software ecosystem in the current landscape of the field of adaptive neuromodulation, and then describes experience with implantation, software integration, and post-surgical validation of recording of brain signals and implant parameters. Initial experience suggests that the hardware capabilities of the BIC device are fully supported by BCI2000, and that the BIC/BCI2000 device can record and process brain signals during free behavior. With further development and validation, the BIC/BCI2000 ecosystem could become an important tool for research into new adaptive neuromodulation protocols in humans.

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