METABOLIC AND CLINICAL-RADIOLOGICAL CHANGES IN PATIENTS WITH SYMPTOMATIC EPILEPSYON THE BACKGROUND OF RUPTURED ANEURYSM IN BRAIN

Abstract

The results of the study of metabolic and clinical-radiological changes in patients of two groups with and without symptomatic epilepsy on the background of hemorrhages from ruptured arterial aneurysms are shown. The findings suggest that there is the development of hypoxic nature of violations with the activation of prooxidant reactions in both groups, however, in patients with symptomatic epilepsy was found a significant decrease in antioxidant activity of enzymatic and non-enzymatic cell protection systems with increasing the production of the proinflammatory cytokine TNF-alpha in contrast to the group of patients without epilepsy.

Keywords

• arterial aneurysm
• cerebral hemorrhage
• symptomatic epilepsy
• ct-angiography
• metabolic parameters