Communications Biology (Aug 2021)
Distinct neuropeptide-receptor modules regulate a sex-specific behavioral response to a pheromone
Abstract
Reilly et al identify a neuropeptide-neuropeptide receptor (NP/NPR) module that is active in male but not in hermaphrodite C. elegans. Using a neuropeptide rescue paradigm, they demonstrate that receptor expression within pre-motor neurons mediates coordination of male-specific and core locomotor circuitries.