Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction

Abstract

Spectroscopic photoacoustic imaging has been limited by wavelength-dependent fluence variations and tissue motion. Here, the authors achieve real-time fluence and motion correction in vivo by using a wavelength-tunable laser, sequential scan of a narrow beam and partial image reconstruction for each pulse.