THE SURGICAL TREATMENT OF PULMONARY TUBERCULOSIS WITH THE RESISTANCE OF MYCOBACTERIA TO DRUGS

Abstract

The results of surgical treatment of 700 patients with preoperatively detected drug resistance are analyzed. The majority of patients were with fibro-cavernous, cirrhotic tuberculosis, chronic empyema, caseous pneumonia (78.1%). Chemotherapy was performed on individual schemes including MBT sensitivity. Glutoxim and Pentaglobin were used as pathogenetic therapy for correction of immunity. Predominant type of resection surgery — 529 (68,6%), surgical interventions — 121 (15.7%), toracostomy or cavernostomy — 54 (7,0%), pleurectomy — 33 (4,3%), operations on the cult of the chief bronchus — 18 (2,3%), mediastinal lymphadenectomy —16 (2,1%). Postoperative complications occurred in 12,9% of cases, mortality was 1,5%. Laboratory established fact of mycobacteria drug resistance had no apparent effect on the number and type of postoperative complications. The results of treatment depended on the prevalence and complications of tuberculosis, concomitant diseases, weakened immune system and the extent of surgical intervention.

Keywords

• pulmonary tuberculosis
• mycobacteria
• immune system