Specific intracellular signature of SARS-CoV-2 infection using confocal Raman microscopy

Hamideh Salehi; Anuradha Ramoji; Said Mougari; Peggy Merida; Aymeric Neyret; Jurgen Popp; Branka Horvat; Delphine Muriaux; Frederic Cuisinier

doi:10.1038/s42004-022-00702-7

Communications Chemistry (Jul 2022)

Specific intracellular signature of SARS-CoV-2 infection using confocal Raman microscopy

Hamideh Salehi,
Anuradha Ramoji,
Said Mougari,
Peggy Merida,
Aymeric Neyret,
Jurgen Popp,
Branka Horvat,
Delphine Muriaux,
Frederic Cuisinier

Affiliations

Hamideh Salehi: LBN, University of Montpellier
Anuradha Ramoji: Friedrich-Schiller-University Jena, Institute of Physical Chemistry and Abbe Center of Photonics (IPC)
Said Mougari: CIRI, International Center for Infectiology Research, INSERM U1111, CNRS UMR5308, Université de Lyon, Université Claude Bernard Lyon, École Normale Supérieure de Lyon
Peggy Merida: Institute of Research in Infectiology of Montpellier (IRIM), University of Montpellier
Aymeric Neyret: CEMIPAI, University of Montpellier
Jurgen Popp: Friedrich-Schiller-University Jena, Institute of Physical Chemistry and Abbe Center of Photonics (IPC)
Branka Horvat: CIRI, International Center for Infectiology Research, INSERM U1111, CNRS UMR5308, Université de Lyon, Université Claude Bernard Lyon, École Normale Supérieure de Lyon
Delphine Muriaux: Institute of Research in Infectiology of Montpellier (IRIM), University of Montpellier
Frederic Cuisinier: LBN, University of Montpellier

DOI: https://doi.org/10.1038/s42004-022-00702-7
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 10

Abstract

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Understanding the mechanisms of virus-induced cell modifications is critical for the development of diagnostics and antiviral treatments. Here, confocal Raman microspectroscopy is demonstrated to be a useful tool to study biochemical modifications in cells caused by SARS-CoV-2 infection.

Published in Communications Chemistry

ISSN: 2399-3669 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Chemistry
Website: https://www.nature.com/commschem

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