Retrospective analysis of patients admitted to our pediatrics outpatient clinic between 2011 and 2015 with a complaint of diarrhea with adenovirus and/or rotavirus positivity

Abstract

INTRODUCTION: Childhood diarrheas are mostly caused by viruses. Enteric viruses (particularly rotavirus and adenovirus) are the most common culprits of acute gastroenteritis. METHODS: A total of 259 children were included in the study, and the patients were divided into two groups: patient group (n = 129) and control group (n = 130). The study group was also sub-divided in three as rotavirus positivity, adenovirus positivity, and both rotavirus + adenovirus positivity. RESULTS: The mean age of the patient group was 21.7 +- 30.0 months, and 60.5% were males. While the presence of diarrhea (p = 0.023) and the number of diarrhea between 0 and 10 (p = 0.001) were statistically higher in the control group, the number of diarrhea between 11 and 15 was statistically higher in the patient group. Rotavirus was positive for 71.3%, adenovirus was positive for 20.2%, both rotavirus + adenovirus were positive for 8.5% in the patient group. There was a statistically strong and significant relation with white blood cell, urea, albumin and C-reactive protein (CRP) values for the patients with rotavirus positivity (p < 0.05). There was a statistically strong and significant relation with diarrhea, vomiting, abdominal pain, and lack of appetite for both three subgroups with rotavirus positivity, adenovirus positivity, and both rotavirus + adenovirus positivity (p < 0.05). DISCUSSION AND CONCLUSION: Based on our study results, we believe that patients with viral gastroenteritis caused by rotavirus and/or adenovirus should be monitored for the development of secondary infections, considering urea, albumin levels, white blood cells, and CRP values.

Keywords

• adenovirus
• child
• gastroenteritis
• rotavirus