Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences

• Theresa Kagermeier,
• Stefan Hauser,
• Kseniia Sarieva,
• Lucia Laugwitz,
• Samuel Groeschel,
• Wibke G. Janzarik,
• Zeynep Yentür,
• Katharina Becker,
• Ludger Schöls,
• Ingeborg Krägeloh-Mann,
• Simone Mayer

Affiliations

Theresa Kagermeier

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany

Stefan Hauser

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany

Kseniia Sarieva

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany

Lucia Laugwitz

Department of Neuropediatrics, Developmental Neurology and Social Pediatrics, University of Tübingen, 72076 Tübingen, Germany

Samuel Groeschel

Department of Neuropediatrics, Developmental Neurology and Social Pediatrics, University of Tübingen, 72076 Tübingen, Germany

Wibke G. Janzarik

Department of Neuropediatrics and Muscle Disorders, Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany

Zeynep Yentür

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany

Katharina Becker

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany

Ludger Schöls

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany

Ingeborg Krägeloh-Mann

Department of Neuropediatrics, Developmental Neurology and Social Pediatrics, University of Tübingen, 72076 Tübingen, Germany

Simone Mayer

Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany