A case of chronic myelomonocytic leukemia complicated with immune thrombocytopenia

Abstract

Chronic myelomonocytic leukemia (CMML) complicated with immune thrombocytopenia (ITP) is rare. This article reports the clinical data of a patient with CMML complicated with ITP treated with a combination of venetoclax, ripertamab (an anti-CD20 monoclonal antibody), and hetrombopag. The coexistence mechanism of CMML and ITP needs to be further clarified. Venetoclax combined with anti-CD20 monoclonal antibody and thrombopoietin receptor agonist may be an effective strategy for the treatment of this complication.

Keywords

• chronic myelomonocytic leukemia
• immune thrombocytopenia
• venetoclax
• hetrombopag
• ripertamab