Robust QRS detection based on simulated degenerate optical parametric oscillator-assisted neural network
Zhiqiang Liao,
Zhuozheng Shi,
Md Shamim Sarker,
Hitoshi Tabata
Affiliations
Zhiqiang Liao
Department of Electrical Engineering and Information Systems, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan; Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan
Zhuozheng Shi
Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan; Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, USA; Corresponding author. Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan.
Md Shamim Sarker
Department of Electrical Engineering and Information Systems, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan; Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan
Hitoshi Tabata
Department of Electrical Engineering and Information Systems, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan; Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan; Corresponding author. Department of Electrical Engineering and Information Systems, Graduate School of Engineering, The University of Tokyo, Tokyo, 113-8656, Japan.
Accurately detecting the depolarization QRS complex in the ventricles is a fundamental requirement for cardiovascular disease detection using electrocardiography (ECG). In contrast to traditional signal enhancement algorithms, emerging neural network approaches have shown promise for QRS detection because of their generalizability on complex data. However, the inevitable noise present during ECG recording leads to a decrease in the performance of neural networks. To enhance the robustness and performance of neural network-based QRS detectors, we propose a simulated degeneration unit (SDU)-assisted convolutional neural network (CNN). An SDU simulates the physical degeneration process of interfering optical pulses, which can effectively suppress in-band noise. Through comprehensive performance evaluations on three open-source databases, the SDU-enhanced CNN-based approach demonstrated better performance in detecting QRS complexes than other recently reported QRS detectors. Furthermore, real-world noise injection tests indicate that the optimal noise robustness boundary for the CNN equipped with SDU is 167–300% higher than that for the CNN without SDU.