CENTRAL HYPOTHROIDISM DUE TO ACUTE LYMPHOBLASTIC LEUKEMIA WITH CENTRAL NERVOUS SYSTEM INFILTRATION

Dilek Kaçar; Seda Şahin; Fatma Burçin Kurtipek; Neşe Yaralı

Hematology, Transfusion and Cell Therapy (Nov 2021)

CENTRAL HYPOTHROIDISM DUE TO ACUTE LYMPHOBLASTIC LEUKEMIA WITH CENTRAL NERVOUS SYSTEM INFILTRATION

Dilek Kaçar,
Seda Şahin,
Fatma Burçin Kurtipek,
Neşe Yaralı

Affiliations

Dilek Kaçar: Ankara City Hospital, Department of Pediatric Hematology and Oncology
Seda Şahin: Ankara City Hospital, Department of Pediatric Hematology and Oncology
Fatma Burçin Kurtipek: Ankara City Hospital, Department of Pediatric Hematology and Oncology
Neşe Yaralı: Ankara City Hospital, Department of Pediatric Hematology and Oncology

Journal volume & issue: Vol. 43
p. S59

Abstract

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Case report: We describe a five-year-old girl with high risk B precursor acute lymphoblastic leukemia with central nervous system involvement. Laboratory tests suggested the presence of central hypothyroidism (thyroid-stimulating hormone [TSH]: 0.30 mU/ml, normal range 0.64–6.27 mU/ml; serum free thyroxine [FT4]: 0.70 ng/dl, normal range 0.86–1.4 ng/dl). Magnetic resonance imaging detected heterogeneous contrast enhancement of pituitary gland in addition to cerebral and cerebellar atrophy.

Published in Hematology, Transfusion and Cell Therapy

ISSN: 2531-1379 (Print); 2531-1387 (Online)
Publisher: Elsevier
Country of publisher: Spain
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the blood and blood-forming organs
Website: https://www.journals.elsevier.com/hematology-transfusion-and-cell-therapy

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