Nature Communications (Apr 2023)

The methylation landscape of giga-genome and the epigenetic timer of age in Chinese pine

  • Jiang Li,
  • Fangxu Han,
  • Tongqi Yuan,
  • Wei Li,
  • Yue Li,
  • Harry X. Wu,
  • Hairong Wei,
  • Shihui Niu

DOI
https://doi.org/10.1038/s41467-023-37684-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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DNA methylation level declines during aging of mammals. Here, the authors report single-base resolution landscape of cytosine DNA methylation at different ages of Chinese pine and show that the global cytosine DNA methylation gradually increases as age progresses.