Clinico-morphological predictors and treatment outcomes in cervical stump cancer

Abstract

The aim of the study is to analyze the characteristics of cervical stump cancer (CSC), identify the clinical and morphological factors influencing prognosis of the disease. Another aim is to study the results of CSC treatment according to the predictive factors. Materials and methods. We have analyzed the treatment results of 150 patients with FIGO stage 0-IIIB metastatic CSC (mCSC). Patients were treated in N.N.Blokhin Russian Cancer Research Center, over the period from 1977 to 2010. Results. We showed that statistically significant predictive factors of mCSC were regional lymph node metastases, stromal invasion greater than 1 cm in depth, stage of disease, the mixed form of tumor growth and the presence of lymph vessel tumor emboli. We also identified that the survival of the patients with histologically verified adenocarcinoma and with the spread of the tumor to the cervical stump was poor. Conclusion. We showed that the risk factors in case of mCSC were the same as in case of cervical cancer.

Keywords

• cervical stump cancer
• morphological predictors
• survival