Pulmonary function tests in type 2 diabetes mellitus

Abstract

Background: Diabetes mellitus is a chronic disease with microvascular and macrovascular complications. Effect of diabetes on lung capacity has been reported previously but with controversial results. This study will help to reassess whether or not Pulmonary Function Tests should be done in diabetics or not. Aim and Objective: Our study aimed to evaluate pulmonary function testing in patients of type 2 diabetes mellitus (T2DM). Study Design: Randomized Case control study. Materials and Methods: 50 diabetics and 50 matched apparently healthy volunteers taken for this study. After taking an informed consent, all underwent screening with detailed history, anthropometry, blood sugar (fasting and post parandial), and pulmonary functions (using medspiror). Statistical Analysis: Student t test was used to compare PFTs of diabetic and control groups. Frequencies were generated for categorical variables and compared with chi square test. Results: There was significant reduction in all the PFT parameters (FVC%, FEV1% and FEV1/FVC) in diabetics as compared to controls. Thus, mixed obstructive-restrictive pattern of pulmonary dysfunction is seen in diabetics. Also strong positive correlation was seen between fasting blood sugar and FEV1/FVC in diabetics. Although body mass index (BMI) was more in study group versus control group, but the difference was not significant. Conclusion: Lungs are indeed effected in patients of diabetes and pulmonary function testing should be mandatory in diabetics in order to prevent complications thereby improving quality of life.

Keywords

• Body mass index
• diabetes
• pulmonary function tests