Arquivo Brasileiro de Medicina Veterinária e Zootecnia (Oct 2012)

Anticoccidial efficacy of drinking water soluble diclazuril in the control of Eimeria acervulina oocysts on experimentally-infected broiler chickens

  • R.C.L. Assis,
  • M.C. Cury,
  • F.D. Luns,
  • R.L. Assis

DOI
https://doi.org/10.1590/S0102-09352012000500016
Journal volume & issue
Vol. 64, no. 5
pp. 1188 – 1193

Abstract

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The experiment was carried out with 150 Cobb broiler chickens divided into 3 groups with 50 birds each. The groups of infected chickens orally received 1ml of inoculum containing 3x103 Eimeria acervulina sporulated oocysts at 12 days of age. Group 1 was kept as a positive control with infected non-medicated birds, group 2 was medicated with diclazuril (1%) with a dose of 1mL/4 L of drinking water for 2 successive days, 5 days after infection, while group 3 was kept as negative control with non-infected and non-medicated birds. Oocysts count per gram of feces, score of macroscopic intestinal lesions and weight gain were evaluated. The group treated with diclazuril showed significant and satisfactory improvement in the assessment criteria when compared to the infected non-medicated group. The results revealed more reduction in the total oocyst count and intestinal lesion score in the medicated than in the infected non-treated group. The results confirmed that (1%) liquid diclazuril is effective to control Eimeria infection.

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