Brain Oxygen Optimization in Severe Traumatic Brain Injury (BOOST-3): a multicentre, randomised, blinded-endpoint, comparative effectiveness study of brain tissue oxygen and intracranial pressure monitoring versus intracranial pressure alone

• Francis Bernard,
• Sharon Yeatts,
• Lori A Shutter,
• William Barsan,
• Ramon Diaz-Arrastia,
• Lisa H Merck

Affiliations

Francis Bernard

Department of Medicine, Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada

Sharon Yeatts

4 Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA

Lori A Shutter

1 Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA

William Barsan

Department of Emergency Medicine, University of Michigan, Ann Arbor, Michigan, USA

Ramon Diaz-Arrastia

Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Lisa H Merck

Emergency Medicine and Neurology, Neurocritical Care, University of Florida College of Medicine, Gainesville, Florida, USA