Einstein (São Paulo) (Jun 2021)

Strategies for hemodynamic maintenance of potential brain-dead donor: integrative review

  • Beatriz Sousa da Fonseca,
  • Verusca Soares de Souza,
  • Taynara Oliveira Farias Batista,
  • Guilherme Malaquias Silva,
  • Dandara Novakowski Spigolon,
  • Neide Derenzo,
  • Aline Barbieri

DOI
https://doi.org/10.31744/einstein_journal/2021rw5630
Journal volume & issue
Vol. 19

Abstract

Read online Read online

ABSTRACT Objective To learn about the scientific production on strategies adopted for hemodynamic maintenance of brain-dead patients. Methods Integrative review with articles published between 2007 and 2019, in Scientific Electronic Library Online (SciELO), Latin American and Caribbean Health Sciences Literature (LILACS), PubMed® and ScienceDirect. The descriptors “ Hemodinâmica AND Morte Encefálica ” and “Hemodynamics AND Brain Death” were used. Exclusion criteria were non-human research and gray literature. Results A total of 21 articles were listed. As strategies, the use of drugs – noradrenaline (n=8), vasopressin (n=7), dobutamine (n=6), hydrocortisone (n=4) and methylprednisolone (n=4); invasive (n=10) and noninvasive (n=13) cardiac monitoring; control of ventilatory parameters (n=12); and correction of fluid and electrolyte disturbances (n=17) were highlighted. Conclusion The main strategies found in this integrative review were regulation of blood pressure and temperature, use of catecholamines and corticosteroids, in addition to the need for an early diagnosis of brain death. However, the lack of clearer protocols on the subject is notorious, making management with the potential donor difficult.

Keywords