Prolonged Response with Enzalutamide in a Prostate Cancer Patient on Hemodialysis

Abstract

Current therapies in oncology that offer a longer and better quality of life are leading to more cases where cancer and chronic diseases coexist. Enzalutamide, a second-generation anti-androgen agent, was approved by the US Food and Drug Administration (FDA) in 2012 for the treatment of metastatic castration-resistant prostate cancer (mCRPC). There is no series with many patients on the use of enzalutamide in patients with end-stage renal disease (ESRD). We present a patient diagnosed with mCRPC who was followed up with enzalutamide treatment for about 5 years after progression with docetaxel and who was on hemodialysis 3 days a week.

Keywords

• enzalutamid
• prostat kanseri
• böbrek yetmezliği
• enzalutamide
• prostate cancer
• renal failure