Nature Communications (Jul 2024)

A droplet robotic system enabled by electret-induced polarization on droplet

  • Ruotong Zhang,
  • Chengzhi Zhang,
  • Xiaoxue Fan,
  • Christina C. K. Au Yeung,
  • Huiyanchen Li,
  • Haisong Lin,
  • Ho Cheung Shum

DOI
https://doi.org/10.1038/s41467-024-50520-9
Journal volume & issue
Vol. 15, no. 1
pp. 1 – 16

Abstract

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Abstract Robotics for scientific research are evolving from grasping macro-scale solid materials to directly actuating micro-scale liquid samples. However, current liquid actuation mechanisms often restrict operable liquid types or compromise the activity of biochemical samples by introducing interfering mediums. Here, we propose a robotic liquid handling system enabled by a novel droplet actuation mechanism, termed electret-induced polarization on droplet (EPD). EPD enables all-liquid actuation in principle and experimentally exhibits generality for actuating various inorganic/organic liquids with relative permittivity ranging from 2.25 to 84.2 and volume from 500 nL to 1 mL. Moreover, EPD is capable of actuating various biochemical samples without compromising their activities, including various body fluids, living cells, and proteins. A robotic system is also coupled with the EPD mechanism to enable full automation. EPD’s high adaptability with liquid types and biochemical samples thus promotes the automation of liquid-based scientific experiments across multiple disciplines.